ANTI-MTOR (MTAB1) 200UL

货号： 07-231      产品名称： ANTI-MTOR (MTAB1) 200UL   品牌： Millipore 规格： EA 三周到货 生化实验

Anti-mTOR (mTAb1) Antibody
Close
REFERENCES
Consecutive bouts of diverse contractile activity alter acute responses in human skeletal muscle.
Vernon G Coffey,Henriette Pilegaard,Andrew P Garnham,Brendan J O’Brien,John A Hawley (2009) Journal of applied physiology (Bethesda, Md. : 1985).106
Effect of high-frequency resistance exercise on adaptive responses in skeletal muscle.
Vernon G Coffey, Donald W Reeder, Graeme I Lancaster, Wee Kian Yeo, Mark A Febbraio, Ben B Yaspelkis, John A Hawley (2007) Medicine and science in sports and exercise.39:2135-44
Attenuation of mammalian target of rapamycin activity by increased cAMP in 3T3-L1 adipocytes.
Scott, P H and Lawrence, J C (1998) J. Biol. Chem., 273: 34496-501 (1998)
Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway.
Scott, P H, et al. (1998) Proc. Natl. Acad. Sci. U.S.A., 95: 7772-7 (1998)
View All
Species Reactivity Key Applications Host Format Antibody Type
H, M, R  IP, EA, WB Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-mTOR (mTAb1) Antibody
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Trade Name:
Upstate (Millipore)
Product Overview:
mTOR is also known as FRAP or RAFT
Specificity:
Recognizes mTOR.
Molecular Weight:
240 kDa
Immunogen:
peptide (C-DTNAKGNKRSRTRTDSYS) corresponding to amino acids 2433-2450 of rat mTOR, mammalian target of rapamycin
Isotype:
IgG
Species Reactivity:
Human
Mouse
Rat
Control:
BDNF activated mTOR in dendritic, neural lysates or synaptoneurosomes
Quality Assurance:
routinely evaluated by immunoblot on RIPA lysates from 293T cells transfected with mTOR
Purification Method:
Immunoaffinity purified
Presentation:
Protein A Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
Storage Conditions:
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
UniProt Number:
P42345
Entrez Gene Number:
NM_004958
Gene Symbol:
FRAP1
RAPT1
MTOR
FRAP
mTOR
FLJ44809
FRAP2
RAFT1
View All »
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
View All »
Key Applications:
Immunoprecipitation
Enzyme Assay
Western Blotting
Entrez Gene Summary:
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The CDT6 gene is located in an intron of this gene.
View All »
UniProt Summary:
FUNCTION: SwissProt: P42345 # Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. Part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cy -20℃