09-120   RCE1, RBX-200UG   品牌 Millipore

RCE1, RBX-200UG

货号: 09-120      产品名称: RCE1, RBX-200UG   品牌: Millipore 规格: EA 三周到货 生化实验

Anti-Rce1 Antibody
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REFERENCES
Mutational analysis of the ras converting enzyme reveals a requirement for glutamate and histidine residues
Plummer, Lisa J, et al (2006) J Biol Chem, 281:4596-605 (2006)
A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation
Maske, Christopher P, et al (2003) J Cell Biol, 162:1223-32 (2003)
Human Ras converting enzyme endoproteolytic specificity at the P2′ and P3′ positions of K-Ras-derived peptides
Hollander, Irwin J, et al (2003) Biochim Biophys Acta, 1649:24-9 (2003)
Species Reactivity Key Applications Host Format Antibody Type
H, M  WB Rabbit Affinity Purified Polyclonal Antibody
Description:
Anti-Rce1 Antibody
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Trade Name:
Upstate (Millipore)
Molecular Weight:
36 kDa (actual M.W.~50 kDa. due to prenylation)
Immunogen:
KLH-conjugated synthetic peptide (SVSRPERPPESAALG-C) corresponding to amino acid 13-27 of human Rce1, Ras converting enzyme 1.
Isotype:
IgG
Species Reactivity:
Human
Mouse
Quality Assurance:
Routinely evaluated by immunoblot.
Purification Method:
Immunoaffinity purified
Presentation:
200 µL (0.5 mg/mL) of immunoaffinity purified rabbit IgG in 0.02M PBS, 0.25M sodium chloride containing 0.1% sodium azide and 50% glycerol.
Storage Conditions:
Stable for 2 years at -20°C from date of shipment.
UniProt Number:
Q9Y256
Entrez Gene Number:
NM_001032279.1
NM_005133.2
Gene Symbol:
RCE1
FACE2
RCE1B
FACE-2
RCE1A
hRCE1
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Alternate Names:
Ras Converting Enzyme 1
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Entrez Gene Summary:
This gene encodes an integral membrane protein which is classified as a member of the metalloproteinase family. This enzyme is thought to function in the maintenance and processing of CAAX-type prenylated proteins.
UniProt Summary:
FUNCTION: SwissProt: Q9Y256 # Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1.
SIZE: 329 amino acids; 35833 Da
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity).
TISSUE SPECIFICITY: Ubiquitous.
SIMILARITY: SwissProt: Q9Y256 ## Belongs to the peptidase U48 family.
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Brand Family:
Upstate
Product Name:
Anti-Rce1 Antibody
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
200 µL
Format:
Affinity Purified
Host:
Rabbit
Applications:
This Rce1 antibody is validated for use in WB for the detection of the Rce1 protein.

-20℃